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Cancer — Male Reproductive System

★ CMTO Exam Focus

Male reproductive system cancers include malignancies of the prostate, testicles, penis, and scrotum. Prostate cancer is the leading cause of cancer death in men, while testicular cancer is the most common cancer in males aged 15-35. Prostate cancer symptoms mimic benign prostatic hyperplasia (BPH), often delaying detection until metastasis. Inguinal lymph nodes are the sentinel nodes for male genital cancers.

Pathophysiology

  • Prostate cancer: Malignant cells in the prostate gland. Tumors require testosterone to grow. Commonly spreads to bladder, rectum, and pelvic/inguinal lymph nodes. Bony metastasis to vertebral column, ribs, and pelvis is frequent
  • Testicular cancer: Germ cell tumors account for 90% — seminomas (slow-growing, radiation-sensitive) and nonseminomas (aggressive). Cryptorchidism is the only consistent risk factor
  • Penile cancer: Typically squamous cell carcinoma. Associated with HPV and uncircumcised status
  • Scrotal cancer: High rate of metastasis to lymph nodes. Linked to occupational tar/soot exposure
  • Prostate cancer symptoms mimic BPH (frequency, urgency, nocturia), delaying detection

Signs and Symptoms

Hallmark Indicators

  • Prostate: Early stages often asymptomatic. Later: restricted urinary flow, hematuria, blood in ejaculate, persistent bone pain in pelvis/spine
  • Testicular: Painless lump or enlargement of one testicle (most common presenting sign). Heaviness or dull ache in lower abdomen/groin. Occasional gynecomastia from hCG-secreting tumors
  • Constitutional: Unexplained weight loss, persistent fatigue, drenching night sweats
  • Deep, aching bone pain in pelvis or spine worse at night (indicates metastasis)

Red Flags and Rule-Outs

  • Painless testicular lump in a young male: Immediate medical referral — do not delay
  • Hematuria (blood in urine) or difficulty starting urinary flow: Common to both BPH and prostate cancer — requires medical evaluation
  • Deep bone pain in pelvis or spine, worse at night: Indicates metastatic spread. High fracture risk
  • Any unexplained lump >5 cm: Immediate referral
  • Gynecomastia in a young male: May indicate hCG-secreting testicular tumor

MT Considerations

  • Goal: Palliative support to manage pain, anxiety, insomnia, and depression
  • Brachytherapy: Clients undergoing brachytherapy (radioactive pellets for prostate cancer) should delay massage until pellets are removed
  • Bone fragility: Prostate cancer frequently metastasizes to vertebral column, ribs, and pelvis. Extreme caution with pressure
  • Lymphedema risk: Inguinal lymph node removal creates lifelong risk of lower extremity lymphedema
  • Psychosocial impact: Treatment often involves side effects (erectile dysfunction, sterility, orchiectomy). Massage provides nurturing touch for altered body image and emotional distress
  • Self-examination counseling: Encourage regular monthly testicular self-examination for early detection
  • Treatment side effects: See chemotherapy and radiation-therapy

CMTO Exam Relevance

  • Prostate cancer symptoms mimic BPH. Hematuria or difficulty starting urinary flow requires medical evaluation
  • Testicular cancer is the most common cancer in males aged 15-35. Cryptorchidism is the primary risk factor
  • Inguinal lymph nodes are the sentinel nodes for male genital cancers
  • PSA and DRE are primary prostate cancer screening tools
  • Seminomas are slow-growing and radiation-sensitive. Nonseminomas are more aggressive
  • A painless testicular lump requires immediate referral

Key Takeaways

  • Prostate cancer is the leading cause of cancer death in men. Its symptoms mimic BPH, delaying detection
  • Testicular cancer is the most common cancer in males aged 15-35 with a high cure rate if caught early
  • Prostate cancer frequently metastasizes to bone (vertebral column, ribs, pelvis). Extreme caution with pressure
  • Brachytherapy patients must delay massage until radioactive pellets are removed
  • Inguinal lymph node removal creates lifelong lymphedema risk in the legs

Sources

  • Rattray, F., & Ludwig, L. (2000). Clinical massage therapy: Understanding, assessing and treating over 70 conditions. Talus Incorporated.
  • Werner, R. (2016). A massage therapist's guide to pathology (6th ed.). Books of Discovery.
  • Norris, T. L. (2019). Porth's essentials of pathophysiology (5th ed.). Wolters Kluwer.